Pain from Multiple Sclerosis? Here's how to get relief


LearnBrain & nervous systemManaging relapsing multiple sclerosisPain from Multiple Sclerosis? Here's how to get relief
Nipping neuropathic pain in the bud
Dialing down dysesthesias like the ‘MS hug’
Lessening lhermitte's sign
Managing musculoskeletal pain
Moving to beat musculoskeletal pain
Prioritizing your mental health

1 of 7

If you live with multiple sclerosis (MS), there’s a good chance you are familiar with pain. It can manifest in many different ways, whether it’s a random twitch or muscular pain that’s developed over years.

When it comes to physical symptoms, MS pain is either musculoskeletal or neuropathic, says Brian Steingo, MD, a neurologist in Boca Raton, Florida. Not all MS pain is physical, though; MS can also affect your mental health.

Whichever type of pain you are managing, these physician-approved methods may help your symptoms.

Sources: MS Trust. Trigeminal neuralgia. February... + 11
  1. MS Trust. Trigeminal neuralgia. February 5, 2026.
  2. MS Trust. Nerve pain (neuropathic pain). November 19, 2025.
  3. National MS Society. Pain and Itching. Accessed September 14, 2026.
  4. National MS Society. Adaptive Clothing for Multiple Sclerosis. June 24, 2025.
  5. MS Trust. Lhermitte’s sign. February 7, 2024.
  6. MS International Federation. Pain. March 13, 2025.
  7. Cleveland Clinic. Lhermitte’s sign. December 14, 2023.
  8. MS Trust. MS pain. November 19, 2025.
  9. MS Society. Lhermitte’s sign. October 1, 2025.
  10. National MS Society. Massage and Bodywork. Accessed September 14, 2026.
  11. Multiple Sclerosis Association of America. Treatments for MS Pain. July 29, 2026.
  12. National MS Society. Emotional Changes. Accessed September 14, 2026.
Written by Ashley Vogt Davids.
Medically reviewed by Joanne Perron, MD, MPH.July, 2026
Updated onSeptember, 2026

Featured content

Condition Cloud: RRMS (subpage)
Interactive

Condition Cloud: RRMS (subpage)

Managing migraines when you have MS
Article

Managing migraines when you have MS

Learn about the connection between migraines, headaches, and multiple sclerosis.

Can meditation help you cope with MS?
Article

Can meditation help you cope with MS?

How this ancient practice may help you cope with the many demands of living with multiple sclerosis.

Why does relapsing-remitting MS progress?
Article

Why does relapsing-remitting MS progress?

Answers about disease progression, diagnosis and treatment for progressive MS.

4 ways to work out when you have multiple sclerosis
Article

4 ways to work out when you have multiple sclerosis

These four types of MS exercises may help boost your strength, mobility, mood and more.

7 strategies for living with multiple sclerosis
Article

7 strategies for living with multiple sclerosis

Living with MS can be a challenge, but there are a number of things you can do to make it easier.

Why diet makes a difference when you have MS
Article

Why diet makes a difference when you have MS

How diet can help you improve energy levels and how to make changes to your diet safely.

The multiple types of multiple sclerosis
Article

The multiple types of multiple sclerosis

Learn about the different patterns of MS.

Sharing your multiple sclerosis (MS) diagnosis
Article

Sharing your multiple sclerosis (MS) diagnosis

Here’s what to consider when disclosing your MS to friends, loved ones, children, and employers.

Multiple sclerosis and the risk of depression
Article

Multiple sclerosis and the risk of depression

Learn how to untangle the overlapping symptoms of multiple sclerosis and depression.

Getting your MS under control
Video

Getting your MS under control

Neurologist Vincent Macaluso, MD, shares ways you can take control of your MS to best fit your lifestyle.

What can I expect if I have just been diagnosed with MS?
Video

What can I expect if I have just been diagnosed with MS?

Many people who are newly diagnosed with relapsing-remitting multiple sclerosis can expect a long life without disability.

What are the different forms of multiple sclerosis?
Video

What are the different forms of multiple sclerosis?

Learn the most common form of multiple sclerosis, relapsing-remitting MS, and how relapsing types of MS differ from progressive forms of MS.

The role of lesions in multiple sclerosis (MS)
Video

The role of lesions in multiple sclerosis (MS)

Vincent Macaluso, MD, explains the role of lesions in MS and how they can range in severity.

5 ways to reduce relapse with RRMS
Video

5 ways to reduce relapse with RRMS

RRMS is the most common form of MS and is characterized by attacks, or relapses, of new and worsening neurological symptoms.

Get a good night's sleep with Multiple Sclerosis
Slideshow

Get a good night's sleep with Multiple Sclerosis

Find relief from common MS symptoms—and finally rest easy.

AskMD by Sharecare LogoAskMD by Sharecare Logo
Privacy policyConsumer health data privacyTerms of use
Cookie policyYour privacy choices

© 2026 Sharecare, Inc.

ask-mdask-md
AskMD by Sharecare LogoAskMD by Sharecare Logo
Privacy policyConsumer health data privacyTerms of use
Cookie policyYour privacy choices

© 2026 Sharecare, Inc.