Treatment options for immune thrombocytopenia (ITP)


LearnCancerImmune thrombocytopenia (ITP) resource centerTreatment options for immune thrombocytopenia (ITP)
Corticosteroids
Immunoglobulin
Immunosuppressant drugs
Other medications
Surgery

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Immune thrombocytopenia (ITP) is a condition where the immune system targets and destroys platelets. Platelets are small cell pieces in the blood that form clots to stop bleeding when there is an injury. ITP causes platelet counts to become too low, which can result in numerous bleeding symptoms. These can include bleeding excessively from injuries, bruising easily, or bleeding for no noticeable reason.

ITP is different for everyone. In some cases, the only treatment required is monitoring. Patients who experience a bleed or injury may require hospitalization and platelet transfusions.

For others, low platelet counts from ITP can persist for years and require ongoing therapy. The right treatment for ITP will depend on a number of factors, including a person’s:

  • Age
  • Platelet count
  • Symptoms
  • Medical history
  • Career
  • Lifestyle

Here are different treatment options for adults who have been diagnosed with ITP.

Sources: National Organization for Rare Disorders... + 13
  1. National Organization for Rare Disorders. Immune Thrombocytopenia. Updated July 12, 2022.
  2. NIH: National Heart, Lung, and Blood Institute. Immune Thrombocytopenia. Updated March 24, 2022.
  3. Cines DB, Bussel JB. How I treat idiopathic thrombocytopenic purpura (ITP). Blood. 2005 Oct 1;106(7):2244-51.
  4. Merck Manual Professional Version. Immune Thrombocytopenia. Reviewed May 2024.
  5. Mayo Clinic. Immune Thrombocytopenia. June 8, 2023.
  6. NHS Inform. Corticosteroids (steroids). Updated May 31, 2024.
  7. Khan AM, Mydra H, Nevarez A. Clinical Practice Updates in the Management Of Immune Thrombocytopenia. P T. 2017 Dec;42(12):756-763.
  8. Cleveland Clinic. Corticosteroids. Reviewed January 20, 2020.
  9. Platelet Disorder Support Association. Immunosuppressants. Accessed October 10, 2024.
  10. Iowa Healthcare. Idiopathic thrombocytopenic purpura. Reviewed March 2017.
  11. DailyMed. Tavalisse—fostamatinib tablet. Updated August 29, 2024.
  12. Siegal D, Crowther M, Cuker A. Thrombopoietin receptor agonists in primary immune thrombocytopenia. Semin Hematol. 2013 Jan;50 Suppl 1(0 1):S18-21.
  13. MedlinePlus. Post-splenectomy complications. Reviewed February 2, 2023.
  14. Immunize.org. Vaccinations for Adults without a Spleen. January 19, 2024.
Written by Jameson Kowalczyk.
Medically reviewed by Mark Arredondo, MD.October, 2024
Updated onAugust, 2026

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