When to seek a second opinion for advanced endometrial cancer

Second opinions can be valuable in the treatment of endometrial cancer, especially when the cancer is at an advanced stage, if the cancer has not responded to treatment, or if the cancer has recurred after treatment.

A second opinion means working with a healthcare provider or team other than the healthcare team you are currently working with. This team will meet with you, review all information related to your diagnosis (including medical records, test results, and pathology reports), and may order additional tests. Based on the information they’ve gathered and reviewed, they will recommend next steps in treatment.

A second opinion may support your initial healthcare team’s recommendations, or it might offer a different approach on how the cancer can be treated.

When and why to consider a second opinion

There are many reasons people seek second opinions. They may want to try working with a different healthcare team with a different communication style. Their health insurance provider may require a second opinion before approving certain treatments. They may have a rare subtype of cancer, have unanswered questions about a diagnosis, or feel overwhelmed by treatment decisions.

Some situations where a second opinion is recommended:

If endometrial cancer is advanced stage

Advanced endometrial cancer refers to stage III and stage IV cancers that have spread beyond the uterus. Advanced can mean locally advanced or metastatic:

• Locally advanced cancers have spread from the uterus into nearby tissues, organs, or lymph nodes.
• Metastatic cancers have spread from the uterus to distant sites in the body, such as the lungs or bones.

The process of treating endometrial cancer becomes more complex when the cancer is more advanced. It often involves combining several types of therapy. It is highly individualized, with each treatment plan tailored to an individual’s diagnosis, goals, and needs.

Second opinions can offer more insight into reviews, pathology reports, and other test results that are used to guide treatment.

If the cancer has not responded to treatment or returned

If the cancer is not responding to treatment or has returned after treatment, you and your healthcare team will need to decide on a different approach to treatment.

Many healthcare providers recommend getting a second opinion before starting treatment. This includes starting second line therapies—therapies that are used when cancer does not respond to an initial therapy.

If you’re seeking access to newer treatment options

While treatment options for advanced endometrial cancer have expanded, newer treatment options are unevenly distributed across the healthcare system. Access to treatment remains a significant barrier for many people.

Getting a second opinion from a different healthcare team may provide insight into additional treatment options. Some healthcare teams may be more experienced with newer treatment options or clinical trials.

If you want a second opinion

If you feel that a second opinion is something that could make a difference in your treatment, pursue a second opinion. Everyone can benefit from a second opinion in some way. Many people also seek second opinions at the encouragement of loved ones and friends.

How to get started getting a second opinion

You’ve decided to seek a second opinion. Your first step in this process will be finding a healthcare provider or team that can give you a second opinion. You will want to work with a gynecological oncologist or an interdisciplinary team that specializes in the treatment of endometrial cancer.

• Start by talking with your current healthcare team. Your oncologist or oncology social worker may be able to provide a list of gynecological oncologists or medical centers.
• Your current healthcare team can also provide copies of test results, medical records, and any treatments you’ve been prescribed—information that you will need for a second opinion.
• Check with your insurance provider about coverage for second opinions. You can also search your insurance provider’s website for in-network gynecological oncologists or centers.
• Use your social support network. Ask friends, family members, or people you’ve met through support groups if they have recommendations.
• Some cancer centers and specialized teams can consult with you remotely, which can be helpful if you do not live close to one of these centers and travel will be difficult.
• Prepare for your appointment by making a list of concerns, questions, and topics you want to discuss with the healthcare provider where you are getting a second opinion.

How will your oncologist feel about a second opinion?

You want to have a good working relationship with your healthcare team, and it’s normal to wonder if getting a second opinion will offend your current healthcare team. Do not let this idea discourage you from seeking a second opinion. Second opinions are common, are an opportunity to learn more about a diagnosis, and your healthcare providers’ ultimate goal is to ensure you get the best care possible.