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4 heart attack signs women should know

Women may not recognize these symptoms as signs of a heart attack.

Jan 18, 2026
Home page>Cardiology>Heart Attack>4 heart attack signs women should know
Written byPatrick Sullivan
Medically reviewedbyAnn Wendling, MD, MPHin February 2024
Slide 1
Unusual fatigue
Indigestion and heartburn
Pain in the neck, jaw, arms, stomach or back
Nausea and vomiting
What to do
Take steps to reduce your risk
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Slide 1

Heart disease is the leading killer of women in the United States, responsible for 1 in 3 deaths each year. Tens of thousands of those deaths are caused by heart attacks. Heart attacks occur when the flow of oxygen-rich blood to the heart muscle is blocked. If the blockage isn’t treated quickly, heart muscle begins to die, and healthy tissue is replaced with scar tissue. 

Evidence shows that women often wait longer than men to call for help during a heart attack, which can be fatal or result in more serious or lasting problems. In one December 2018 study published in European Heart Journal: Acute Cardiovascular Care, researchers found that on average, it took women 37 minutes longer than men to dial an ambulance for a heart attack.  

One reason for this discrepancy may be that women downplay their symptoms or just don’t realize they need urgent medical attention. They are also less likely than men to have “classic” symptoms, like chest pain. Women tend to experience lesser-known heart attack symptoms, too, such as shortness of breath, nausea, vomiting, fatigue, or breaking out into a cold sweat, which could be confused with another condition, such as the flu or heartburn or indigestion.  

Every second is important when you're having a heart attack. Delays in treatment increase the risk for worse outcomes. Don't ignore these four heart attack symptoms in women.

Sources (20)
  1. American Heart Association. 2022 Heart Disease & Stroke Statistical Update Fact Sheet Females & Cardiovascular Diseases. 2022.
  2. Mozaffarian D, Benjamin EJ, et al. Heart Disease and Stroke Statistics—2016 Update: A Report From the American Heart Association. Circulation. 2016;133:e38–e360
  3. National Heart, Lung, and Blood Institute. What Is Coronary Heart Disease? Last updated March 24, 2022.
  4. Meyer MR, Bernheim AM, Kurz DJ, et al. Gender differences in patient and system delay for primary percutaneous coronary intervention: current trends in a Swiss ST-segment elevation myocardial infarction population. European Heart Journal: Acute Cardiovascular Care. 2019;8(3):283-290.
  5. Centers for Disease Control and Prevention. Heart Disease: Heart Attack Symptoms, Risk, and Recovery. Reviewed January 9, 2024.
  6. American College of Cardiology. Seeking Treatment Earlier May Improve Heart Attack Outcomes. January 4, 2016.
  7. Cleveland Clinic. 3 Heart Attack Signs Women Shouldn’t Ignore. October 26, 2021.
  8. Harvard Health Publishing. Heart attacks in women. December 16, 2019.
  9. Mayo Clinic. Symptoms: Fatigue. December 2, 2020.
  10. National Heart, Lung, and Blood Institute. What Is a Heart Attack? Last updated March 24, 2022.
  11. MedlinePlus. Heartburn. Reviewed January 30, 2023.
  12. National Institute of Diabetes and Digestive and Kidney Diseases. Definition & Facts of Indigestion. Last reviewed November 2016.
  13. American Heart Association. Heartburn or heart attack? Last reviewed April 16, 2018.
  14. American Heart Association. Heart Attack Symptoms in Women. Last reviewed July 31, 2015.
  15. MedlinePlus. Nausea and vomiting – adults. Reviewed July 1, 2021.
  16. Johns Hopkins Medicine. Heart Attack. Accessed September 22, 2022.
  17. American Heart Association. Aspirin and Heart Disease. Last reviewed March 20, 2019.
  18. American Heart Association/American Stroke Association. When Minutes Matter Systems of Care for Acute Cardiovascular Conditions. 2013.
  19. Centers for Disease Control and Prevention. Heart Disease: Know Your Risk for Heart Disease. Last reviewed December 9, 2019.
  20. Johns Hopkins Medicine. Smoking and Cardiovascular Disease. Accessed February 21, 2024.
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