Digestive healthGut healthNutrition

5 worst things you're doing to your gut

Keeping your gut bacteria happy may lead to better overall health.


LearnDigestive healthGut health5 worst things you're doing to your gut
Not taking antibiotics as directed
Not getting enough movement
Smoking
Not managing stress
Eating an unhealthy diet

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It’s estimated that about 39 trillion bacterial cells reside in the human body, the vast majority in the colon. Together with other microbes, these bacteria make up the gut microbiome.

Scientists know the microbiome aids in digestion and influences our immune and nervous systems. But they’re only beginning to understand the extent to which it affects our health overall. Recent studies suggest that gut bacteria may also shape our risk of developing a range of conditions, including obesity, diabetes, and some cancers. The research, however, is largely new and limited in scope, and has been done mostly on animals.

“It’s in its relative infancy compared to other aspects of medical science,” says R. Stuart Bridge, MD, a gastroenterologist in Salt Lake City. “And clinical applications of this kind of knowledge of the microbiome are still being developed.”

In the meantime, we can help the most beneficial members of the microbiome flourish—in terms of numbers and variety—by practicing a healthy lifestyle and avoiding some potentially detrimental habits. Here are some of the worst things you can do for your gut and its community of helpful bugs.

Sources: Sender R, Fuchs S, & Milo R. Revised Est... + 18
  1. Sender R, Fuchs S, & Milo R. Revised Estimates for the Number of Human and Bacteria Cells in the Body. PLoS Biology. August 2016. 14(8), e1002533.
  2. Abbott A. Scientists bust myth that our bodies have more bacteria than human cells. Nature. 08 January 2016.
  3. U.S. Department of Veterans Affairs. How a Healthy Gut Makes for a Healthier You. June 5, 2017. Accessed May 2, 2022.
  4. Foster JA, Rinaman L, & Cryan JF. Stress & the gut-brain axis: Regulation by the microbiome. Neurobiology of Stress. December 2017, 7, 124–136.
  5. Singh RK, Chang HW, et al. Influence of diet on the gut microbiome and implications for human health. Journal of Translational Medicine. 2017; 15: 73.
  6. Harvard Health Publishing. Can gut bacteria improve your health? October 2016. Accessed May 2, 2022.
  7. Langdon A, Crook N, & Dantas G. The effects of antibiotics on the microbiome throughout development and alternative approaches for therapeutic modulation. Genome Medicine. 2016; 8(1), 39.
  8. Mohr AE, Jäger R., et al. The athletic gut microbiota. Journal of the International Society of Sports Nutrition. 2020. 17(1), 24.
  9. Mach N & Fuster-Botella D. Endurance exercise and gut microbiota: A review. Journal of Sport and Health Science. June 2017. Volume 6, Issue 2, Pages 179-197.
  10. Douglas Main. Rugby Player Study Suggests Exercise Diversifies Gut Bacteria. Popular Science. June 11, 2014.
  11. Monda V, Villano I, et a. Exercise Modifies the Gut Microbiota with Positive Health Effects. Oxidative Medicine and Cellular Longevity. 2017, 3831972.
  12. Savin Z, Kivity S, et al. Smoking and the intestinal microbiome. Archives of Microbiology. 2018 Jul;200(5):677-684.
  13. Lee SH. Intestinal permeability regulation by tight junction: implication on inflammatory bowel diseases. Intestinal Research. January 2015. 13(1), 11–18.
  14. GI Society. The Effects of Smoking on Inflammatory Bowel Disease. 2015. Accessed May 2, 2022.
  15. American Psychological Association. That gut feeling. September 2012. Accessed May 2, 2022.
  16. Saulnier DM, Ringel Y, et al. The intestinal microbiome, probiotics and prebiotics in neurogastroenterology. Gut Microbes. January 2013. 4(1), 17–27.
  17. Holscher HD. Dietary fiber and prebiotics and the gastrointestinal microbiota. Gut Microbes. 2017; 8(2), 172–184.
  18. Sawicki CM, Livingston KA. et al. Dietary Fiber and the Human Gut Microbiota: Application of Evidence Mapping Methodology. Nutrients. February 2017; 9(2), 125.
  19. Costantini L, Molinari R, et al. Impact of Omega-3 Fatty Acids on the Gut Microbiota. International Journal of Molecular Sciences. December 2017; 18(12), 2645.
Written by Kristen Sturt.
Medically reviewed by Ann Wendling, MD, MPH.February, 2024
Updated onAugust, 2026
Written by Kristen Sturt.
Medically reviewed by Ann Wendling, MD, MPH.February, 2024
Updated onAugust, 2026
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