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Can testosterone gel affect your partner?

Learn what to do if you’re concerned about topical testosterone therapy affecting someone close to you.

Apr 4, 2025
Home page>Endocrinology>Hypogonadism>Can testosterone gel affect your partner?
Written byJameson Kowalczyk
Medically reviewedbyMark Arredondo, MDin April 2025
Updated onApril 4, 2025

Testosterone is a male hormone that plays a significant role in sexual health and functioning, bone density, blood cell counts, muscle mass, and cognitive function. As with other hormones, the body requires the right amount of testosterone to function well and stay healthy.

When levels of testosterone are too low, problems can occur. These can include a loss of libido, erectile dysfunction, loss of muscle mass, accumulation of body fat, fatigue, and mood changes. Low testosterone can also contribute to conditions like osteoporosis and depression.

These symptoms and the potential for complications lead many people to consult a healthcare provider and seek treatment for low testosterone.

Treatment for low testosterone is broadly referred to as testosterone replacement therapy, or TRT. A commonly prescribed TRT comes in the form of topical gels.

Testosterone gels

These gels are applied to the skin. They allow testosterone to be absorbed into the body and boost testosterone levels.

Gels are applied directly to the skin each day. They take between two and five hours to fully absorb. During that time, a person must avoid showering, swimming, or contact with others.
 
There are several different gels available, and instructions on dosing and application will differ between specific products.

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Risk of transfer

Testosterone gels are also a cause for concern. While the treatment is meant for the user alone, there is a risk that the medication can be spread to others through physical contact or from clothing, where it can be absorbed into that person’s skin.

There are accounts of women and children being exposed to testosterone gel. This can lead to symptoms such as hair growth on the face or other areas of the body, deeper voice, significant increase in acne, enlarged sex organs, aggressive behavior, and bone problems. It can also result in birth defects if a person who is pregnant comes into contact with the gel, and it can be harmful to infants if transferred through breastfeeding.

Avoiding transfer to others

There are steps a person can take avoid transmitting testosterone medication to others. The first step is to carefully read the safety information included with the testosterone gel. The safety information will have detailed instructions on how to use and how to store this medication, as well as precautions to take to avoid spreading it to others.

Here are some other precautions to take:

  • Wash hands immediately after applying a testosterone gel.
  • After applying the gel, cover the area where it was applied with a t-shirt or other clothing.
  • Wear gloves if applying testosterone gel to another person.
  • If you are going to be in close physical contact with others, shower beforehand.
  • Keep any clothing that might have come into contact with the gel separated.

This is also a topic that you should discuss with your healthcare provider.

Other options for TRT

If you are concerned about the potential risks of using a topical testosterone gel, you might consider switching to a different type of TRT. There are many available, including oral medications, transdermal patches, injections, subcutaneous implants, and nasal gels.

As always, your healthcare provider will be your best source of information. They can help you better understand the risks and potential benefits of different therapies and choose one that is best for you.

Sources (10)
  1. Harvard Health Publishing. Treating low testosterone levels. August 9, 2019.
  2. Cleveland Clinic. Low Testosterone (Male Hypogonadism). September 2, 2022.
  3. MedlinePlus. Testosterone Topical. October 15, 2018.
  4. GoodRx. Testosterone gel (AndroGel). Accessed April 2, 2025.
  5. Jane Ridley. A 2-year-old showed signs of puberty after he was exposed to his dad's testosterone gel. He developed pubic hair and his height was off the charts. Insider. June 15, 2022.
  6. de Ronde W. Hyperandrogenism after transfer of topical testosterone gel: case report and review of published and unpublished studies. Hum Reprod. 2009 Feb;24(2):425-8.
  7. Emilio Garcia Garcia and Ignacio Jimenez Varo. Potential consequences in children of a testosterone gel used by their fathers. Endocrinologia, Diabetes y Nutricion (English ed.), 2017.    Vol. 64, No. 5.
  8. Mayo Clinic. Testosterone (Topical Application Route). February 1, 2025.
  9. HealthyMale.org.au. Ask the Doc: Can my partner absorb the testosterone in testosterone gel when applying it to me?
  10. F. Yuen, S. Wu, et al. Preventing secondary exposure to women from men applying a novel nestorone/testosterone contraceptive gel. Andrology, 2019. Vol. 7, No. 2.
  • Testosterone gels
  • Risk of transfer
  • Avoiding transfer to others
  • Other options for TRT
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