Mental healthStress reliefGeneral wellness

9 things everyone should know about depression (even if you're not depressed)

It can affect anyone, aggravate pain, and worsen heart disease. But that’s not all.


LearnMental health9 things everyone should know about depression (even if you're not depressed)
How much of depression is genetic?
Can anyone become depressed?
Am I having a few bad days, or is it depression?
How can depression affect me physically?
How can I tell someone I'm depressed?
What treatment is available for depression?
How does therapy work?
Can I do anything to help my depression at home?
How can I help a loved one with depression?

1 of 10

Despite increased awareness in recent years, depression remains difficult to talk about for many people. The mood disorder, which causes persistent sadness and loss of interest, is common and can affect anyone at any age. In fact, about 18 percent of United States adults report being diagnosed at some point, according to the Centers for Disease Control and Prevention (CDC).

Depression shouldn’t be something you have to silently struggle with. Here’s what you should know about its genetic component, the difference between depression and sadness, how to best seek treatment, and more.

Sources: Lee B, Wang Y, Carlson SA, et al. Nation... + 15
  1. Lee B, Wang Y, Carlson SA, et al. National, State-Level, and County-Level Prevalence Estimates of Adults Aged ≥18 Years Self-Reporting a Lifetime Diagnosis of Depression — United States, 2020. MMWR Morb Mortal Wkly Rep 2023;72:644–650.
  2. Centers for Disease Control and Prevention. National Center for Health Statistics. Depression. Reviewed November 6, 2023.
  3. Chand SP, Arif H. Depression. StatPearls Publishing. January 2023.
  4. National Institute of Mental Health. Depression. Last reviewed September 2023.
  5. Centers for Disease Control and Prevention. Vital Signs: Adverse Childhood Experiences. Updated August 23, 2021.
  6. Mayo Clinic. Depression (major depressive disorder). October 14, 2022.
  7. Frank P, Batty GD, Pentti J, et al. Association Between Depression and Physical Conditions Requiring Hospitalization. JAMA Psychiatry. 2023;80(7):690–699.
  8. Mayo Clinic. Pain and depression: Is there a link? April 3, 2019.
  9. Centers for Disease Control and Prevention. Diabetes: Diabetes and Mental Health. Reviewed May 15, 2023.
  10. American Heart Association. How Does Depression Affect the Heart? Reviewed June 22, 2021.
  11. You Matter: 988 Lifeline. Talking About Depression. Accessed January 12, 2024.
  12. Substance Abuse and Mental Health Services Administration (SAMHSA). Depression. Updated April 4, 2023.
  13. American Psychological Association. Overcoming depression: How psychologists help with depressive disorders. Updated March 7, 2023.
  14. American Psychological Association. Depression. Accessed January 12, 2024.
  15. Mayo Clinic. Depression: Supporting a family member or friend. April 5, 2023.
  16. National Health Service (NHS UK). How to help someone with depression. Reviewed August 18, 2022.
Written by Ediva Zanker.
Medically reviewed by Joanne Perron, MD, MPH.January, 2024
Updated onAugust, 2026
Written by Ediva Zanker.
Medically reviewed by Joanne Perron, MD, MPH.January, 2024
Updated onAugust, 2026
AskMDAskMD

Curious about Mental health?

Get instant answers from our AI health assistant

Ask Now

Recommended for you

Certain health issues, like heart disease and diabetes, may increase the risk for depression. Find out why.

4 health risks linked to depression
Slideshow

In the U.S., more than 19 million people are affected by depression.

What you need to know about depression
Article

Here are seven depression red flags you might not know about.

7 depression symptoms you shouldn't ignore
Article

Learn what increases the odds that you or a loved one will experience major depressive disorder.

8 risk factors for major depressive disorder
Article

Learn about the different kinds of this mental health issue, plus ways to help protect your emotional well-being.

What to know about types of depression
Article
AskMDHow can I be more consistent?
AskMD by Sharecare LogoAskMD by Sharecare Logo
Privacy policyConsumer health data privacyTerms of use
Cookie policyYour privacy choices

© 2026 Sharecare, Inc.

ask-mdask-md
AskMD by Sharecare LogoAskMD by Sharecare Logo
Privacy policyConsumer health data privacyTerms of use
Cookie policyYour privacy choices

© 2026 Sharecare, Inc.