Mental health

7 questions to ask about major depression

Your healthcare provider’s answers can help you get the treatment you need.

Jan, 2026
LearnPsychiatryMajor depression7 questions to ask about major depression
Slide 1
Do I have major depression?
Why am I depressed?
Is stress or illness causing my depression?
What treatments are available?
What about medication side effects?
What should I do (or not do) during treatment?
What can I expect at follow-up visits?

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Slide 1

If you've been diagnosed with major depression (also called clinical depression, major depressive disorder, or MDD) or think you could have it, you may have a lot of questions, like how it’s treated and what to expect from treatment. Understanding everything you can about major depression and talking openly with your healthcare provider (HCP) is the first step toward recovery. Start managing your depression symptoms by learning the answers to these seven important questions.

Written byMichael Gollust.
Medically reviewed byAmy Gonzales, MD.October, 2025
Sources: MedlinePlus. Major Depression. April 19 + 6
  1. MedlinePlus. Major Depression. April 19, 2025.
  2. National Institute of Mental Health. Depression. 2024.
  3. Anxiety and Depression Association of America. Depression. December 22, 2025.
  4. American Psychiatric Association. What Is Depression. April 2024.
  5. Mayo Clinic. Depression (Major Depressive Disorder). October 14, 2022.
  6. Mayo Clinic Staff. Selective Serotonin Reuptake Inhibitors (SSRIs). September 11, 2024.
  7. National Health Service. Antidepressants. June 12, 2025.

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