General wellnessProstate health

The 10 deadliest men’s health conditions

Learn the biggest reasons most American men die, and how you can decrease your risk.

Jan, 2026
LearnUrologyMale reproductive system diseaseThe 10 deadliest men’s health conditions
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#10: Chronic liver disease
#9: Influenza and pneumonia
#8: Alzheimer's disease
#7: Suicide
#6: Diabetes
#5: Stroke
#4: Chronic lower respiratory disease
#3: Unintentional Injuries
#2: Cancer
#1: Heart disease

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From heart disease to drug overdoses to pneumonia, these 10 conditions and events cause about 3 of every 4 male deaths in the United States, claiming the lives of around 1 million men in 2015 alone. 

Read on to find out what they are, and how they specifically affect men. Plus, learn how to identify symptoms, get treatment and, in some cases, reduce your risk of dying.

Written byKristen Sturt.
Medically reviewed byMark Arredondo, MD.April, 2025

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