What is sickle cell disease?

Sickle cell disease results from a hemoglobin mutation. In this video, HealthMaker Gary Gibbons, MD, director of the National Heart, Lung, and Blood Institute, describes why sickle cell disease is so debilitating.

Why red blood cells are so important, and how these cells are affected by sickle cell disease.

This severe infection can lead to long-term complications—and even death—if not treated quickly and effectively.

Healthy eating and boosting your calorie intake can help support your treatment.

Terms that can help you make sense of what is happening in the body when a person has PNH.

Learn about the key differences between these distinct diseases with similar names.